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    Home»Sports»Week 3 NFL best bets, betting analysis, picks and props
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    Week 3 NFL best bets, betting analysis, picks and props

    By Olivia CarterSeptember 19, 2025No Comments8 Mins Read0 Views
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    Week 3 NFL best bets, betting analysis, picks and props
    Why Yates sees 'boom potential' for George Pickens in Week 3 (0:56)

    Field Yates explains why he loves George Pickens' fantasy upside vs. the Bears in Week 3. (0:56)

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    • Matt Bowen

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      Matt Bowen

      ESPN Writer

        Matt Bowen is a fantasy football and NFL writer for ESPN. He joined ESPN in 2015, writes regularly for ESPN+ and spent multiple years on “NFL Matchup.” After graduating from the University of Iowa, Matt played safety in the NFL for St. Louis, Green Bay, Washington and Buffalo over seven seasons.
    • Seth Walder

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      Seth Walder

      ESPN Analytics

        Seth Walder is an analytics writer at ESPN, specializing in quantitative analysis. He is also a regular on “ESPN Bet Live” and helps cover sports betting. Seth has been at ESPN since 2017. He previously worked at the New York Daily News covering the Jets and Giants. You can follow Seth on X via @SethWalder.

    Sep 19, 2025, 01:30 PM ET

    Value is value, no matter where — or how — you find it. And that’s what we’ll aim to do each week in this space — find value.

    Ben Solak is out this week, so Matt Bowen is filling in with his own unique style.

    Bowen and Seth Walder bring different perspectives into how they approach sports betting. A former NFL safety, Bowen predicts positive matchups and game winners from tape study and his understanding of the league. Walder relies on statistical models to pick out plus-expected value bets.

    These weekly picks will not be limited to a certain bet type. From spreads and money lines to totals or even defensive player props, a good price might be found anywhere.

    Results will be tracked throughout the season, with flat one-unit wagers for each listed bet. As always, odds are from ESPN BET Sportsbook.

    With that, let’s dive into Week 3.

    Note: Walder’s defensive prop bets will be added as they become available.

    Jump to:
    Game bets | Offensive props

    Game bets

    Dallas Cowboys at Chicago Bears total points OVER 50.5 (-115)

    The Dallas defense lacks impact players. You can see that on the tape. And I’m looking at a Bears unit that is struggling to find a pass rush, while injuries are already pilling up at the second and third level. Through two weeks, Dallas is allowing 6.4 yards per play (29th in the league), with Chicago checking in at 7.2 (31st), and both defenses are giving up over 30 points per game. Bad football. Dallas will have pass-game matchups to exploit in this one, and I wouldn’t be surprised if Caleb Williams posts his best numbers of the season on Sunday at Soldier Field. Take the over. — Bowen

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    Philadelphia Eagles to cover -3.5 (Even) vs. Los Angeles Rams

    We know the Eagles need to create more explosive plays in the pass game. Through two weeks, Jalen Hurts is completing 75.6% of his throws, but he’s averaging only 5.6 yards per attempt. Now, there will be opportunities to scheme versus the Rams’ split-safety and Cover 3 zone looks this Sunday, so let’s get A.J. Brown and DeVonta Smith loose over the top. But I’m still taking the Birds here because of the offensive front and the run game. Remember, Saquon Barkley produced over 200 yards rushing in each of the two matchups versus the Rams last season. Win with the foundational approach on the ground, while increasing the shot play throws for Hurts. That’s Eagles football. — Bowen

    Green Bay Packers (ML) at Cleveland Browns and Tampa Bay Buccaneers (ML) vs. New York Jets in two-team parlay (-166)

    I see Green Bay and Tampa Bay as locks this week, so let’s ensure them in a two-team parlay.

    The Packers’ pass rush — with the addition of Micah Parsons — has generated a pressure rate of 40% (third highest in the league), and they have eight sacks (tied for second most). Plus, they have matchup advantages on the edges versus the Browns’ offensive tackles. With Joe Flacco’s reduced mobility, this feels like a game where Green Bay dictates from a defensive perspective.

    In the Tampa Bay matchup, Justin Fields is out (concussion), so we will see Tyrod Taylor manage the offense. However, Taylor and the Jets need to find an efficient run game, which isn’t easy versus the Bucs’ defensive front. Through two games, Tampa is allowing only 3.3 YPC, which sets up their pressure packages on third downs. Lean on the Tampa defense here and bet on Baker Mayfield to win the critical moments — again. — Bowen

    Offensive player props

    play

    1:30

    Why D’Andre Swift is an easy start in fantasy vs. Cowboys

    Mike Clay explains why D’Andre Swift is an easy start in fantasy as the Bears take on Cowboys in Week 3.

    CeeDee Lamb to go OVER 82.5 receiving yards (-115)

    Lamb has topped the 100-yard receiving mark in both games played this season, and the Bears will be without No. 1 corner Jaylon Johnson and slot corner Kyler Gordon due to injuries. Lamb will have matchup advantages from both slot and boundary alignments. And if the Bears do roll with a more zone-heavy script, look for Lamb to find open grass as a catch-and-run target for quarterback Dak Prescott. — Bowen

    George Pickens to score anytime touchdown (+130)

    Let’s stay with the Chicago-Dallas matchup here and bet on Pickens finding the end zone. Pickens caught his first touchdown of the season in the Week 2 win over the Giants, and he has already seen five end zone targets over his first two games. With his vertical stretch ability, Pickens can get loose on shot-play throws, or the Cowboys can isolate him in the low red zone. Take the bet versus a beat-up Bears secondary. — Bowen

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    Tyler Lockett to record 50+ receiving yards (+900)

    The start of the season has been so ugly for Lockett that AP Style dictates I still have to spell out his production numbers: four targets, two receptions, nine yards. But while his playing time is down from where it was in Seattle last year, he’s still on the field a decent amount. Lockett has run routes on 60% of Tennessee’s dropbacks this season. And the target here, 50 receiving yards, is really not asking that much. I get that it was a different situation a year ago, but Lockett hit 50 receiving yards five times last year, and we’re now getting +900 for him to do it on Sunday. This line is too pessimistic about the veteran receiver, according to my receiving yards model. It makes the fair price here +405. — Walder

    Cedric Tillman to record 90+ receiving yards (+750)

    Tillman is playing a ton, running routes on 92% of Cleveland Browns dropbacks (even slightly more often than Jerry Jeudy). He’s running high-value routes, too — deep crossers and digs that tend to produce higher yards per route run numbers. Granted, Tillman’s yards per route run on the increased playing time have not been inspiring (0.8), but considering the playing time he’s getting and that the Browns will almost certainly be playing from behind and therefore throwing a fair amount, this is too good of a price to pass up. My model makes this +381. — Walder

    D’Andre Swift to go OVER 2.5 receptions (-125)

    We’re 3-1 on these bets, and I see no reason why we shouldn’t keep it rolling. The premise is simple: when defenses play zone coverage, they allow receptions to running backs almost twice as frequently as when they play man coverage. The theory here is that this isn’t fully baked into the betting market, and so we’re backing running backs facing zone defenses and fading those facing man defenses. Through two weeks, the defense that stands out in this regard is absolutely the Cowboys; they are playing zone coverage at a massive 86% rate (no team played zone more than 72% over the course of last season). So Swift’s reception over is an easy choice in Week 3. — Walder

    TreVeyon Henderson to record 20+ yards receiving (-135)

    Against a Steelers defense that is giving up an average of 25.5 yards receiving to running backs, look for Henderson to see targets on screens and unders, while coordinator Josh McDaniels schemes for the rookie on backfield releases to attack linebackers in coverage. Henderson has produced at least 24 yards receiving in both games played this season, so I like this bet to hit on Sunday. — Bowen

    Tyler Warren to go OVER 50.5 yards receiving (-115)

    Indianapolis head coach Shane Steichen has a dedicated plan for Warren in the route tree. Warren has produced at least 75 yards receiving in each of his first two pro games, with at least seven targets in both. And Steichen is setting Warren up as a multilevel option for quarterback Daniel Jones — with room to run after the catch. He can rumble in the open field. Take the over in the Week 3 game versus Tennessee. — Bowen

    Trevor Lawrence to go UNDER 0.5 INTs thrown (+115)

    I’m actually at -117 here, so this is a decent-sized discrepancy in a market where my model is usually quite close to the betting odds. One obvious reason why we’re getting +115 on the under: Lawrence has thrown three picks this season. Picks are fluky, however, and so we really ought to look at the Jacksonville Jaguars quarterback through a longer lens. Last season he recorded a 2.2% interception rate, slightly above the 1.9% league average but hardly an outlier. Another factor that stands out here is how run-heavy the Jaguars have been, ranking 25th in pass rate over expectation per NFL Next Gen Stats. That limits the number of throws Lawrence will be expected to make and, in turn, reduces the chance of an interception. — Walder

    Others to consider:

    Analysis bets betting NFL picks props week
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    Olivia Carter
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    Olivia Carter is a staff writer at Verda Post, covering human interest stories, lifestyle features, and community news. Her storytelling captures the voices and issues that shape everyday life.

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